• Thứ 7, 11/07/2020
  • (GMT+7)
Gía trị cộng hưởng từ phổ trong chẩn đoán ung thư tuyến tiền liệt

Gía trị cộng hưởng từ phổ trong chẩn đoán ung thư tuyến tiền liệt

03/25/2020 22:33:20 | 0 binh luận

The value of magnetic resonance spectroscopy in diagnosis of prostate cancer

SUMMARY

Purpose: The aim of study was to determine the value of MRS in diagnosis of prostate carcinoma especially for differentiating begnin from malignant lesion of the prostate.

Materials and methods: During a period of 4/2014 to 6/2016, 25 consecutive patients with elevated PSA level or clinical suspiciousness were evaluated with MRS of the prostate. The results were confirmed by TRUS-guided biopsy. We compare two groups (prostate carcinoma/PCa and prostate non-caricnoma/PNCa) by variant: mean of the choline plus creatine -to- citrate. Analyzing ROC curve to find the value of MRS in differentiating begnin from malignant tissue of the prostate.

Results: Patients range in age from 40 to 89 years (mean 71 ± 12 year). 08 patients were confirmed to have PNCa (32%), whereas 17 patients had PCa (68%). The mean of (Cho+ Cr)/Ci values for PNCa and PCa were 0.50± 0.31 and 2.64± 1.22 respectively. The mean of (Cho+Cr)/ Ci value of PCa was significantly higher than PNCa (p<0.05). On ROC curve, using discrimination threshold of (Cho+Cr)/ Ci is 0.84, the MRS provided a sensitivity of 94.1%, specificity of 87.5% for differentiating NPCa from PCa.

Conclusion: Magnetic Resonance Spectroscopy of the prostate can be use to differentiate begnin from malignant tissue with high accuracy.

Key words: Prostatic carcinoma, non-carcinoma, Magnetic resonance spectroscopy, TRUS.

Nghiên cứu đặc điểm hình ảnh cộng hưởng từ hoại tử vô khuẩn chỏm xương đùi ở những bệnh nhân có chỉ định thay khớp háng

Nghiên cứu đặc điểm hình ảnh cộng hưởng từ hoại tử vô khuẩn chỏm xương đùi ở những bệnh nhân có chỉ định thay khớp háng

04/01/2020 16:17:40 | 0 binh luận

Study the magnetic resonance imaging characteristics in patients with hip joint repiacement indicattion

SUMMARY

Objectives:

1) Characterization of magnetic resonance images aseptic necrosis of the femoral head in patients with hip replacement appointed.

2) Characterization of magnetic resonance images of the contralateral hip in patients people on.

Objects and methods of research: Retrospective study of 60 patients with aseptic necrosis of the femoral head surgery during 2014- 2015 at a hospital in Hanoi Medical University and Hospital Vietnam Germany.

Results: The patients having hip replacement appointed two phase III and IV. All patients had femoral head collapse and are mostly seen when patients have hip osteoarthritis secondary (75% stage IV). Hypointense region was 73.3% stage III, stage IV, 93.3%, in line with a high prevalence of bone marrow showing the progression of the disease is> 85%. Rate aseptic necrosis of the femoral head in the contralateral hip joint meeting with the high rate of 80%, occur in all phases. Photos CHT at an early stage (I and II) are more common form hypointense band (77.4%), bone marrow lesions form T1-weighted images are shaped ring (61.3%), lesions of the subclass A (74.2%). Late stage (III and IV) characteristic image is under the cartilage fracture and femoral head collapse, besides that other image: hypointense on T1-weighted images region (70.5%), the image of subclass D (52.9%).

Conclusions: MRI allows an accurate assessment stage lesions of clinical help for prognosis and hip replacement decision at the right time, at the same time to detect aseptic necrosis of the femoral head in the contralateral hip though no clinical symptoms, so that early treatment measures or prevent the more severe complications.

Keywords: Aseptic necrosis of the femoral head.

Chất tương phản MRI - PRIMOVIST: Vai trò trong chẩn đoán thương tổn gan

Chất tương phản MRI - PRIMOVIST: Vai trò trong chẩn đoán thương tổn gan

03/22/2020 19:18:01 | 0 binh luận

The role of hepatobiliary specific MR cantrast agent in the diagnostic focal liver lesion

SUMMARY

Purpose: Assessing the role of hepatobiliary - specific MR contrast Agent in the detection and differentiation of benign and malignant focal liver lesions. Maximizing accuracy of imaging in the context of focal liver lesions is paramount in avoiding unnecessary biopsies, which may result in post-procedural complications.

Methods and Materials: Retrospectively evaluated the 200 patients cases, executed hepatic MRI at Medic Medical center wich hepatobiliary - specific MR contrast Agent. From on January 2013 to on January 2016, age range 28 - 72years. The lesion detected in liver: 65 cases HCC, 5 Metastasis, 2 cholangiocarcinoma, 2 Adenoma, 26 FNH, 24 Hemangiomas, 14 Regenerative nodules, 20 cysts, 5 Abscess, 37cases had normal liver. All the patients executed T2WI fatsat, Diffusion weighted imaging - MRI with three b values (0, 500, 800 sec/mm2) and Dynamic with Primovist contrast media on the Siemens Avanto 1,5T MRI.

Results: In 65cases MRI HCC: 8 cases <1cm; 32 cases 1-2cm; 25 cases >25cm. 26 cases biopsic result: 24 cases HCC (92%), 2 cases cholangiocarcinoma, 39 cases TOCE or RFA no biopsy. 5 cases metastas detected primary tumor. 2 cases cholangiocarcinoma are right with biopsic result. 2 cases adenoma: 1case biopsic resulted in adenoma, 1 case follow up over 1year. 25 cases hemangiomas with contrast media from peripheral enhancement progressing to centre of lesion; 12 cases regenerative nodules is follow up over 1 year no change in nodule size; 20 cysts are high-signal intensity like fluid - signal on the T2WI, T1WI, Diffusion and no change of intensity is found after contrast injection; in 5 cases abscess: 3 cases recovered from an illness, 2 cases HCC after biopsy.

Conclusion: Magnetic resonance imaging executed with hepatobiliary - specific MR contrast Agent, contributed to detect the small lesion and differential diagnosis between benign and malignant tumor of the liver.

Cộng hưởng từ tuyến vú ở bệnh nhân ung thư vú thể ẩn có di căn hạch nách

Cộng hưởng từ tuyến vú ở bệnh nhân ung thư vú thể ẩn có di căn hạch nách

04/03/2020 09:02:31 | 0 binh luận

Mr imaging of the breast in patients with occult primary breast cancer presenting as an axillary metastasis

SUMMARY:

Purpose: To access the value of MRI in the diagnosis of occult primary cancer with axillary metastasis.

Methods and Materials: 12 patients occult breast cancer with malignant axillary adenopathy and negative on mammographic, echography and physical examination findings, were underwent contrast material-enhanced MR imaging in Hanoi medical university hospital.

Results: The sensitivity of MRI in the diagnosis of occult primary cancer with axillary metastases was 83%. MR imaging depicted small cancers from 3 to 12mm diameter. Of the 12 patients, three patients were underwent mastectomy, five were underwent lobectomy, and four were underwent breast-conservation therapy.

Conclusion: MR imaging is very sensitive for the detection of occult breast cancer with malignant axillary adenopathy. MR imaging offers potential not only for cancer detection but also for staging the cancer within the breast, which may be useful for treatment planning. Keywords: dynamic breast MRI, occult breast cancer

Vai trò của ADC trong chẩn đoán phân biệt giữa tổn thương lành tính và ác tính ở gan

Vai trò của ADC trong chẩn đoán phân biệt giữa tổn thương lành tính và ác tính ở gan

03/31/2020 15:24:03 | 0 binh luận

summary

Purpose: Assessing the role of Apparent Diffusion Coefficient (ADC) measurement in differentiation of benign and malignant focal hepatic lesions.

Methods and Materials: Retrospectively evaluated the 248 patients cases, executed hepatic MRI at Medic Medical center, from on February 2011 to on February 2013, age range 41 - 78years, with 142 benign hepatocellular lesions (30 FNHs, 9 HCAs, 63 hemangiomas and 40 cysts) and 104 malignant lesions (76 HCC and 28 metastasis) diagnosed, 50 patients had normal liver. All the patients executed Diffusion weighted imaging - MRI with three b values (0, 500, 800 sec/mm2) on the Siemens Avanto 1,5T MRI.

Results: We found difference between ADC of benign lesions compared with malignant lesions (mean ± standard deviation): ADC of normal liver (1.242 × 10−3 mm2/sec ± 0.33), FNH-HCA (1.742 × 10−3 mm2/sec ± 0.40), Hemangiomas (2.084 × 10−3 mm2/sec ± 0.46), Cyst (2.861 × 10−3 mm2/sec ± 0.34), HCC (1.093× 10−3 mm2/sec ± 0.37), Metastasis (1.126 × 10−3 mm2/sec ± 0.48). ADC of benign lesions: (2.327 × 10−3 mm2/sec ± 0.41), compared with malignant lesions: (1.113 × 10−3 mm2/sec ± 0.39).

Conclusion: Mean value of apparent diffusion coefficient (ADC) contribute to differential diagnosis between benign and malignant focal hepatic lesions.

Ung thư gan vỡ, xuất huyết ổ bụng, được trị liệu hóa dầu thuyên tắc mạch qua catheter (TOCE) tai bệnh viện Hoàn Mỹ Đà Nẵng: Nhân một trường hợp

Ung thư gan vỡ, xuất huyết ổ bụng, được trị liệu hóa dầu thuyên tắc mạch qua catheter (TOCE) tai bệnh viện Hoàn Mỹ Đà Nẵng: Nhân một trường hợp

03/26/2020 22:18:24 | 0 binh luận

Ruptured hepatocellular carcinoma (hcc), bleeding in abdomen is treated by toce (transcatheter oily chemoembolization) at hoanmy DaNang hospita: a case report

SUMMARY

- HCC is the most common of cancer liver.

- Nature progress, metastasis is complex, multiple organs.

- Ruptured HCC, Bleeding in abdomen, hypotention, shock,...: is severe statement, progress is very rapid, complex, serious, dead rate is hight.

- Diagnotic and treatment (TOCE) of ruptured HCC must rapid, exact. Doing everything possible to keep the patient alive !.

- A report of a man patient 79 year olds, at emergency room of Hoan My Da Nang hospital, was diagnosted ruptured HCC, hypotention,…He hadbeen taken emergency abdoment CT and treatmented

– TOCE. The doctors did everything possible to keep him alive.

- Follow- up and consolidate TOCE, crux problem !\

Keyword: Hepatocellular Carcinoma, Computed tomography, Digital Subtraction Angiography, Transcatheter Oily Chemoembolization, Gastrointestinal endoscopy surgery, laparoscopic surgery.

Đặc điểm hình ảnh 18F-FDG PET/CT não ở bệnh nhân Alzheimer và ở người lão hóa bình thường

Đặc điểm hình ảnh 18F-FDG PET/CT não ở bệnh nhân Alzheimer và ở người lão hóa bình thường

03/25/2020 22:45:48 | 0 binh luận

Imaging characteristics of brain 18f-fdg pet/ct in alzheimer’s disease patients and in normal elderly persons

SUMMARY

Purpose: Define 18F-FDG PET/CT cerebral imaging characteristics in Alzheimer’s Disease patients and in the normal elderly persons (Nls).

Objects and Methods: From 2014 to 2015, 26 Alzheimer’s disease patients and 20 normal elderly persons undergone brain 18F-FDG PET/CT scans.

Results: Mean age of Alzheimer’s disease patients is 66,3±8,2 years old and 64,2±8,1 in Nls. Homogenous 18F-FDG cerebral uptake in Nls. Most of cerebral regions in Alzheimer’s disease patients suffering from a reduction of mean SUV. Rate of 18F-FDG hypometabolism in medial temporo-hippocampal area in 96.2% of cases on left side, meanwhile 92.3% of cases having a hypometabolism in right medial temporo-hippocampal area as well as in bilateral posterior cingulate gyrus, 76.9% in temporo-parietal area on right side and 86.5% on left side. Cerebral metabolism in occipital lobes principally reserved. Hypometabolism affecting bilateral frontal lobe in a half of cases. Brain glucose metabolism partially reserved at primary moto-sensory cortices, cerebellum, as well as in anterior cingulate gyrus, especially reservation of glucose metabolism at basal ganglias in Alzheimer disease (96,2%). Rate of glucose hypometabolic Alzheimer like patterns in 92,3% of cases with 84,6% on both sides.

Conclusion: No focal cerebral cortical hypometabolism in Nls. Evident reduction in 18F-FDG uptake of cerebral cortices in Alzheimer’s disease patients in compared with Nls. Imaging characteristics of hypometabolism in 18F-FDG PET/CT brain scan in Alzheimer’s disease patients are regional anatomically and specifically with high rate in medial temporo-hippocampal, posterior temporal, temporo-parietal and posterior cingulate areas, well correspondent to wellknown glucose metabolic patterns in Alzheimer’s disease.

Key words: Alzheimer’s Disease (AD), Brain 18F-FDG PET/ CT, imaging characteristics.

Nghiên cứu các đặc điểm hình ảnh và đánh giá kết quả điều trị dị dạng động - tĩnh mạch tủy bằng can thiệp nội mạch

Nghiên cứu các đặc điểm hình ảnh và đánh giá kết quả điều trị dị dạng động - tĩnh mạch tủy bằng can thiệp nội mạch

03/22/2020 17:29:46 | 0 binh luận

The imaging characteristics and embolization treatment of spinal arteriovenous

SUMMARY

Purpose: to describe the imaging characteristics and the results of spinal arteriovenous shunt treated by endovascular intervention.

Material and Methods: Descriptive and intervention study, patients were diagnosed and treated by endovascular intervention at the Bach Mai hospital from 2012 to 2016. Imaging features were evaluated on MRI and DSA, evaluated of effectiveness of treatment based on the comparison of clinical symtoms, MRI imaging before and after endovascular treatment.

Result: Diagnosis and endovascular intervention of 20 patients. On MRI, the sign of spinal cord edema and dilated venous drainage were spotted in almost patients. The rate of complete angiographic obliteration was 60% patients and partial in 45.5% patients. After follow up of 3-6 months, spinal cord damage reduce accounted 88.23% and 11.77% patients remain unchanged, clinically significance improvement was achieved in 82.35% patients,17.65% patients do not improve (3 cases are continous following).

Conclusion: MRI plays an important role in the diagnosis and follow up patients with spinal arteriovenous shunt, DSA is the gold standard for diagnosis and to allow intervention treatment with high effective.

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